Predictive value of Hcy on contrast-induced nephropathy after PCI in patients with acute myocardial infarction
10.3969/j.issn.1673-4130.2017.19.018
- VernacularTitle:血浆Hcy对急性心肌梗死患者PCI术后发生造影剂肾病的预测价值
- Author:
Fang WANG
1
;
Peng LI
;
Xizhe ZHAO
;
Ting TIAN
Author Information
1. 北京电力医院心血管内科
- Keywords:
homocysteine;
contrast media;
neohropathy;
acute myocardial infarction;
percutaneous coronary interven-tion
- From:
International Journal of Laboratory Medicine
2017;38(19):2705-2708
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of plasma homocysteine (Hcy) on contrast-induced nephropathy after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) .Methods Totally 156 patients with AMI receiving PCI in Beijing Electric Power Hospital from January 2014 to December 2015 were enrolled for the study and divided into contrast-induced nephropathy group and non-contrast-induced nephropathy group .Baseline data ,perioperative data and auxilia-ry examination results were compared between two groups .The single factor analysis and multivariate Logistic regression were used to analyze the influencing factors .Results In all 156 patients ,32 cases occurred contrast-induced nephropathy after PCI ,and the in-cidence was 20 .5% .The plasma Hcy level in contrast-induced nephropathy group was (21 .3 ± 8 .7)μmol/L ,significantly higher than (13 .3 ± 6 .1) μmol/L in non-contrast-induced nephropathy group (P< 0 .05) .Multiple Logistic regression analysis results showed that plasma Hcy levels was the independent risk factors of contrast-induced nephropathy (OR=2 .254 ,95% CI:1 .359 -3 .737 ,P=0 .002) .Conclusion About 1/5 of patients with AMI occur contrast-induced nephropathy after PCI ,and preoperative plasma Hcy level can well predict the risk of contrast-induced nephropathy ,which is worthy of clinical application .
