Application of immunohistochemistry in pathological diagnosis of lymphoproliferative lesions
10.3760/cma.j.issn.1009-9921.2017.10.013
- VernacularTitle:免疫组织化学在淋巴组织增生性病变病理诊断中的应用
- Author:
Meigang ZHU
1
Author Information
1. 510330,广州金域医学检验中心病理组
- Keywords:
Immunohistochemistry;
Lymphoproliferative lesions;
Pathology;
clinical;
Diagnosis
- From:
Journal of Leukemia & Lymphoma
2017;26(10):629-630,640
- CountryChina
- Language:Chinese
-
Abstract:
The immunohistochemistry is an useful method for pathological diagnosis and differential diagnosis of lymphoproliferative lesions,but it must be used correctly and its immunophenotypic results should be evaluated. The following points should be paid attention: (1) Similar antibodies must be reasonable compatibility; (2) the pseudo-positive and pseudo-negative of immunophenotype must be distinguished; (3) the immunophenotypica site must be distinguished; (4) the specify of the antibody expression must be distinguished; (5) the immunophenotype in the tumor cells or reactive cells must be distinguished; (6) the immunophenotype must be used correctly in differential diagnosis between the benign and malignant of hyperplastic lymphoid tissues. The author emphasizes that immunohistochemical techniques need to be combined with other diagnostic features of lymphoproliferative lesions,in order to obtain satisfactory results.
