Clinical significance of peripheral blood leukocytosis in patients with advanced malignant tumors

VernacularTitle:晚期恶性肿瘤患者外周血白细胞计数升高的临床意义
Author: Xufang CHEN ¹ ; Huimin WANG ; Shuang HAN
Author Information

1. 264100,滨州医学院烟台附属医院肿瘤一科
Keywords: Neoplasms; Leukocyte count; Prognosis
From: Cancer Research and Clinic 2017;29(9):611-613,618
CountryChina
Language:Chinese
Abstract: Objective To explore the capability of leukocytosis in predicting the survival time of patients with advanced malignant tumors,in order to provide evidences for clinicians to make the best therapy regimen. Methods The clinical data of 103 dead patients with advanced malignant tumors treated from September 2015 to September 2016 were collected.The relationship between peripheral blood white blood cell count (WBC) and survival time of patients was analyzed retrospectively. The survival analysis was performed by Kaplan-Meier and Log-rank test,and Cox regression was used for multivariate analysis. Results An elevated peripheral blood WBC was found in 61.1%(63/103) dead patients with advanced malignant tumors, and the elevated WBC was negatively correlated with the life span (r=-0.569, P=0.000). Conclusion Elevated WBC in some advanced malignancy patients predicts they are in the end-stage, which can guide clinicians adjust treatment regimens in time,and they may consider palliative care for those patients.