Progress of long non-coding RNA LINC00152 in gastrointestinal cancer
10.3760/cma.j.issn.1006-9801.2017.09.017
- VernacularTitle:长链非编码RNA LINC00152在消化系统肿瘤中的研究进展
- Author:
Wangyang ZHENG
1
;
Zhenglong LI
;
Jinglin LI
;
Xinheng LI
;
Zhidong WANG
;
Xingming JIANG
;
Yunfu CUI
Author Information
1. 150086,哈尔滨医科大学附属第二医院胆胰外科
- Keywords:
Digestive system neoplasms;
Long non-coding RNA;
Long intergenic non-protein-coding RNA 152;
Tumor markers;
biological
- From:
Cancer Research and Clinic
2017;29(9):639-642
- CountryChina
- Language:Chinese
-
Abstract:
With the advance of biology technology, non-coding RNA (ncRNA) has been confirmed to be closely associated with the occurrence and development of the cancer. The ncRNA can be divided into two groups by length, including microRNA (miRNA) and long non-coding RNA (lncRNA). As a member of lncRNA,LINC00152(long intergenic non-protein-coding RNA 152)has been taken into cancer research, which can regulate the activity of miRNA and involve the regulation of gene transcription of gene transcription and protein generation. The characteristics of LINC00152 that correlate with many clinical manifestations and can be detected in liquid biopsies make it becoming new biomarkers of cancer diagnosis. This paper reviews the current progress of LINC00152 in gastrointestinal cancer.
