Advances in detection and clinical application of circulating tumor DNA
10.3760/cma.j.issn.1006-9801.2017.09.019
- VernacularTitle:循环肿瘤DNA检测及临床应用研究进展
- Author:
Yan LI
1
;
Min TAO
;
Hailin LU
Author Information
1. 南通大学附属吴江医院肿瘤科
- Keywords:
Circulating tumor DNA;
Next generation sequencing;
Clinical application
- From:
Cancer Research and Clinic
2017;29(9):645-648
- CountryChina
- Language:Chinese
-
Abstract:
With the development of cancer precision medicine, it is very important to study the detection of tumor driving genes. Because of the difficulty to get tissue biopsy, liquid biopsy especially like circulating tumor DNA (ctDNA) has received extensive attention in recent years. However, many issues have not been completely described. What kinds of approaches have been used for ctDNA detection? How about their sensitivity and specificity are? What their advantages and disadvantages are? What are the clinical applications of ctDNA?This article will summarize these questions.
