Function of circadian rhythms in regulation of metabolism
10.7644/j.issn.1674-9960.2017.07.015
- VernacularTitle:昼夜节律在代谢调控中的作用
- Author:
Chen XING
1
;
Ye GU
;
Lun SONG
Author Information
1. 军事医学科学院基础医学研究所军事应激医学研究室
- Keywords:
circadian rhythm;
circadian clock;
energy metabolism;
metabolic syndrome
- From:Military Medical Sciences
2017;41(7):618-622
- CountryChina
- Language:Chinese
-
Abstract:
The circadian rhythm generated by the endogenous circadian clock system depends on the feedback loop composed of a series of core clock genes (bmal1, clock, cry and per) and clock controlled genes (rev-erbα, rorα, dbp, tef and hlf) .The circadian rhythm is closely related to the body metabolism , which plays important roles in the metabolic process of the major nutrients , such as glucose and fat .Circadian rhythm disorders caused by exogenous factors will significantly increase the risk of metabolic syndrome .This paper focuses on the effect of circadian rhythms on metabolism and their roles in regulating metabolic syndrome .