Pulmonary Placental Transmogrification Presenting as a Small Lung Nodule.
10.3904/kjm.2016.90.2.144
- Author:
Hak Su KIM
1
;
Ji Hyun LEE
;
Hye Cheol JEONG
;
Jung Hyun KIM
;
Su Hyung PARK
;
Ah young KWON
;
Eun Kyung KIM
Author Information
1. Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea. imekkim@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Neoplasm, Lung;
Placenta;
Chorionic villi
- MeSH:
Aged;
Biopsy, Needle;
Chorionic Villi;
Diagnosis;
Female;
Humans;
Lung Diseases;
Lung Neoplasms;
Lung*;
Needles;
Pathology;
Placenta;
Radiography;
Thorax;
Trophoblasts
- From:Korean Journal of Medicine
2016;90(2):144-147
- CountryRepublic of Korea
- Language:English
-
Abstract:
Pulmonary placental transmogrification (PT) is a rare lung disease that takes on the histologic appearance of placental chorionic villi. We herein report a case of PT in a 66-year-old woman who presented with a single nodule on chest radiography performed during a routine health examination. She had no complaints of any symptoms. Chest radiography showed a focal ill-defined nodular opacity in the right lower lobe; chest computed tomography revealed a 17-mm lobulated, focal irregular mass with fissural retraction in the right lower lobe, suggestive of lung cancer. Pathology of a percutaneous needle aspiration biopsy revealed papillary structures resembling placental villi. These were lined by cytotrophoblast-like cells and syncytiotrophoblasts. This characteristic pathologic finding led to a diagnosis of PT. PT of the lung is found mainly in bullous or cystic lesions. However, this patient presented with a single nodule on chest radiography.