Efficacy of salmeterol fluticasone propionate combined with montelukast in the treatment of moderate and severe bronchial asthma
10.3969/j.issn.1005-1678.2017.10.067
- VernacularTitle:沙美特罗替卡松联合孟鲁司特钠治疗中重度支气管哮喘的疗效
- Author:
yan Hai LI
1
;
wei Jin WANG
;
qing Dong LV
;
fei Gui YAO
;
Ling LIN
;
ping Yu LI
Author Information
1. 温州医科大学附属浙江省台州医院 呼吸内科
- Keywords:
bronchial asthma;
salmeterol fluticasone propionate;
montelukast sodium
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):167-168
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of salmeterol fluticasone propionate combined with montelukast in the treatment of moderate and severe bronchial asthma. Methods 112 patients with moderate and severe bronchial asthma in Taizhou hospital from January 2014 to December 2016 were selected and divided into the control and the study group according to the time of visiting hospital, 56 cases in each group. The control group were given salmeterol fluticasone propionate for treatment, the study group were treated with salmeterol fluticasone propionate combined with montelukast .Keep a record of the asthma control test (ACT), forced expiratory volume (FEV1) percentage expected index changes of pre-treatment and 8 weeks after treatment. Results ACT score and FEV1 percentage expected index changes of two groups there was no significant difference before the treatment. After treatment, ACT score and FEV1 percentage expected index changes of the study group was better than the control group(P<0.05). Conclusion Salmeterol fluticasone propionate combined with montelukast in the treatment can significantly improve the clinical efficacy of patients.