Chronic Myeloid Leukemia Relapsing as Isolated Extramedullary Disease Presenting as a Cardiac Mass.
10.3904/kjm.2016.90.2.159
- Author:
Seonggyu BYEON
1
;
Hee Kyung KIM
;
Ji Hoon MOON
;
Seong Mi MOON
;
Jee Eun PARK
;
Silvia PARK
;
Chul Won JUNG
Author Information
1. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. chulwon1.jung@samsung.com
- Publication Type:Case Report
- Keywords:
Chronic myeloid leukemia;
Granulocytic sarcoma;
Cardiac tumor
- MeSH:
Bone Marrow;
Clone Cells;
Heart Neoplasms;
Hematopoietic Stem Cell Transplantation;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*;
Prognosis;
Recurrence;
Sarcoma, Myeloid;
Stem Cell Transplantation
- From:Korean Journal of Medicine
2016;90(2):159-162
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Allogeneic hematopoietic stem cell transplantation is the only option for chemotherapy-refractory chronic myeloid leukemia (CML). Extramedullary relapse after transplantation is rare and usually accompanies marrow relapse. Generally, the prognosis of extramedullary relapse is poor. Here, we report a man with extramedullary relapsed CML after stem cell transplantation that presented as an isolated cardiac mass, which has shown an indolent course for more than 2 years, without evolving to medullary relapse during that period. This case implies that the CML clone might contribute to the development of quiescent extramedullary relapse with a benign course.
