Intrathecal injection of ceftazidime and ceftriaxone in the treatment of 60 cases of intracranial infection after intraventricular drainage
10.3969/j.issn.1005-1678.2017.10.028
- VernacularTitle:鞘内注射头孢他啶与头孢曲松治疗脑室外引流术后颅内感染60例
- Author:
gang Zhi WEN
1
;
jun Ling GENG
Author Information
1. 宁夏医科大学附属吴忠市人民医院 神经外科
- Keywords:
intrathecal injection;
ceftazidime;
ceftriaxone;
intracranial infection;
intraventricular drainage
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):71-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of intrathecal injection of ceftazidime and ceftriaxone in the treatment of intracranial infection after intraventricular drainage. Methods 60 patients with intracranial infection after intraventricular drainage in Wuzhong people's hospital from October 2013 to March 2017 were selected and were divided into reference group and study group by random sampling method, with 30 cases in each group. The reference group was treated with ceftriaxone treatment, the study group was treated with intrathecal ceftazidime and ceftriaxone. The therapeutic effect and adverse reaction rate of the two groups were evaluated. Results The total effective rate of the patients in the study group (96.67%) was significantly higher than that in the reference group (73.33 %), and the adverse reaction rate (3.33%) was significantly lower than that of the reference group (26.66%), and the difference was statistically significant (P<0.05). Conclusion Intrathecal injection of ceftazidime and ceftriaxone in patients with intracranial infection after intraventricular drainage, the treatment effect is obvious, and the incidence of adverse reactions is low, which is worthy of clinical study.
