Efficacy and safety of amiodarone combined with Wenxin Granule in the treatment of unstable angina pectoris complicated with ventricular arrhythmia
10.3969/j.issn.1005-1678.2017.10.079
- VernacularTitle:胺碘酮联合稳心颗粒治疗不稳定型心绞痛并室性心律失常有效性和安全性分析
- Author:
ying Li FENG
1
;
Wei HAO
Author Information
1. 长安区医院 内科
- Keywords:
unstable angina pectoris;
ventricular arrhythmia;
Wenxin Granule;
amiodarone
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(10):191-192
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy and safety of amiodarone combined with Wenxin Granule in the treatment of unstable angina pectoris complicated with ventricular arrhythmia. Methods 80 cases of unstable angina pectoris and ventricular arrhythmia in our hospital were selected, were randomly divided into early death and experimental group, 40 patients in each group. The two groups were treated with antiplatelet therapy, anticoagulant therapy and other symptomatic treatment. The control group was treated with amiodarone, and the experimental group was treated with amiodarone and Wenxin granule. The safety and clinical efficacy of two groups of angina attack times were compared and analyzed. Results The experimental group had ventricular fibrillation and ventricular premature beat probability were 2.50% and 5.00% lower than the control group, the control group had adverse reaction of nausea and vomiting was 11 cases significantly more than the control group, with statistical difference (P<0.05). The experimental group 24 h in myocardial ischemia times (11.34±3.45) times the number was significantly less than the control group (20.80±4.87), the control group during the course of angina frequency (24.50±5.67) was significantly higher than the experimental group, there was significant difference (P<0.05). Conclusion The combination of amiodarone and Wenxin granule is effective and safe in the treatment of unstable angina pectoris complicated with ventricular arrhythmia.