Four Cases of Rhabdomyosarcoma in the Head and Neck.
- Author:
Seung Lyong HA
1
;
Bong Jae LEE
;
Seon Tae PARK
;
Sang Yoon KIM
Author Information
1. Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sykimz@www.amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Rhabdomyosarcoma;
Embryonal;
Head and neck
- MeSH:
Biopsy;
Breast;
Child;
Drug Therapy;
Female;
Follow-Up Studies;
Head*;
Humans;
Incidence;
Induction Chemotherapy;
Male;
Nasal Cavity;
Nasopharynx;
Neck*;
Neoplasm Metastasis;
Rhabdomyosarcoma*;
Rhabdomyosarcoma, Embryonal
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
1998;41(9):1208-1212
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Rhabdomyosarcoma is a highly aggressive malignant tumor with an incidence of 1/500,000 children per year. Head and neck is the most common site of the embryonal rhabdomyosarcoma. We experienced four cases of embryonal rhabdomyosarcoma, each case originating from temporalis muscle, nasal cavity, parapharynx and nasopharynx. The median age of four patients was 12.5 years old (range, 3-25 years), and the male and female ratio was 2:2 . Two patients were treated with operation and postoperative chemotherapy and irradiation. One patient was treated with induction chemotherapy before operation, and then received postoperative chemotherapy and irradiation. The remaining one patient was incidentally confirmed by excisional biopsy and treated with chemotherapy and irradiation. The median follow-up period was 24 months (range, 6-56 months). Three patients recovered completely with no further evidence of disease. One patient showed breast metastasis after 3 months later.
