Intrahepatic Extramedullary Hematopoiesis Mimicking a Hypervascular Hepatic Neoplasm on Dynamic- and SPIO-Enhanced MRI.
- Author:
In Joon LEE
1
;
Se Hyung KIM
;
Dae Sik KIM
;
Jeong Min LEE
;
Joon Koo HAN
;
Byung Ihn CHOI
Author Information
- Publication Type:Case Report
- Keywords: Liver; Extramedullary hematopoiesis; Magnetic resonance (MR); Superparamagnetic iron oxide; Kupffer cell
- MeSH: Adenoma/*diagnosis; Adult; Diagnosis, Differential; *Hematopoiesis, Extramedullary; Humans; Liver/*physiology; Liver Neoplasms/*diagnosis; *Magnetic Resonance Imaging; Male; Primary Myelofibrosis/physiopathology
- From:Korean Journal of Radiology 2008;9(Suppl):S34-S38
- CountryRepublic of Korea
- Language:English
- Abstract: We present a rare case of a focal intrahepatic extramedullary hematopoiesis (EMH) that mimicked a hypervascular hepatic neoplasm in a 33-year-old woman with idiopathic myelofibrosis. The lesion showed homogeneous and persistent enhancement on both contrast-enhanced CT and gadolinium-enhanced dynamic MR imaging. The lesion did not demonstrate an apparent signal drop on a T2*-weighted sequence following administration of a superparamagnetic iron-oxide agent (SHU 555A). A hepatocellular adenoma was the initial radiological diagnosis. To the best of our knowledge, this is the first report of a histopathologically proven intrahepatic EMH evaluated with dynamic- and SPIO-enhanced MRI.
