Reconstruction of Septal Perforation with Alloderm.
- Author:
Heung Man LEE
1
;
Seon Tae KIM
;
Jae Hoon CHO
;
Je Hyuck LEE
;
Choong Sik CHOI
;
Soon Jae HWANG
;
Sang Hag LEE
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea. hmlee91@hotmail.com
- Publication Type:Original Article
- Keywords:
Nasal septal perforation;
Acellular human dermal graft (Alloderm)
- MeSH:
Connective Tissue;
Follow-Up Studies;
Humans;
Inflammation;
Nasal Septal Perforation;
Nasal Surgical Procedures;
Transplants
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2000;43(12):1323-1327
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: The closure of nasal septal perforation is a significant surgical challenge with high failure rates. Acellular human dermal graft (Alloderm) placed between mucoperichondrial advancement flaps may be an alternative. The purpose of this study was to investigate the usefulness of Alloderm for the repair of nasal septal perforation. MATERIALS AND METHODS: Seven consecutive patients with septal perforation who received the septal perforation repair with Alloderm were included in this study. The causes of septal perforations were previous nasal surgeries, trauma, chemical irritation, inflammation, or unknown. Follow-up periods ranged from 7 to 36 months. RESULTS: Six of seven patients had successful outcomes with complete closure of their perforations. The remaining one patient had an incomplete closure, but the size of the performation was reduced with no further symptoms. CONCLUSION: AIloderm can be used as a connective tissue and interpositional grafts in the repair of septal perforations with high success rates. Therefore, Alloderm is the viable alternative for the closure of nasal septal perforations.
