Smoking, Alcohol Intake and the Risk of Dupuytren's Disease in Koreans.
10.4055/jkoa.2007.42.3.305
- Author:
Soo Bong HAHN
1
;
Ho Jung KANG
;
Seung Hwan LEE
;
Hong Kyun KIM
Author Information
1. Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea. sbhahn@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Dupuytren;
Smoking;
Alcohol
- MeSH:
Dupuytren Contracture*;
Follow-Up Studies;
Humans;
Interviews as Topic;
Logistic Models;
Retrospective Studies;
Risk Factors;
Smoke*;
Smoking*
- From:The Journal of the Korean Orthopaedic Association
2007;42(3):305-309
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study evaluated the relationship between Dupuytrens disease and smoking and alcohol intake. MATERIALS AND METHODS: Forty eight patients with Dupuytrens disease, who underwent a partial fasiectomy were examined retrospectively through a chart review and a telephone interview. The minimum follow-up period was 12 months. The relationship between Dupuytren's disease and smoking and alcohol intake were analyzed using multivariate logistic regression with significance set at p<0.05. RESULTS: Dupuytren's disease requiring surgery in these patients was associated with heavy alcohol intake (odds ratio 2.91) and alcohol intake per week (odds ratio 1.22). The average smoking level was 24.7 pack-year for cases compared with 16.1 pack-year for controls (p<0.05). The average alcohol intake was 3.0 units per week for the cases compared with 1.2 units per week for controls (p<0.05). Smoking was not an independent risk factor but increased the risk when combined with heavy alcohol intake. CONCLUSION: Heavy alcohol intake is an independent risk factor of Dupuytren's disease in Korean. Smoking is not an independent risk factor but increases the risk when combined with heavy alcohol intake.
