Treatment Results and Prognostic Factors of T3 Supraglottic Cancer.
- Author:
Jun Mo KIM
1
;
Hyung Jin KIM
;
Sung Bae CHOI
;
Chang Haeng LEE
;
Seung Kuk BAEK
;
Soon Young KWON
;
Kwang Yoon JUNG
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, Korea University, College of Medicine, Seoul, Korea. kyjung@kumc.or.kr
- Publication Type:Original Article
- Keywords:
Supraglottic cancer;
Transglottic cancer;
Prognosis;
Survival rate
- MeSH:
Dyspnea;
Humans;
Laryngoscopy;
Lymph Nodes;
Neck Dissection;
Neoplasm Metastasis;
Prognosis;
Retrospective Studies;
Survival Rate;
Vocal Cords
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2002;45(5):506-510
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: To analyze results of treatment and prognostic factors in patients with T3 supraglottic carcinoma and to compare results of treatment in patients with T3 transglottic carcinoma with T3 pure supraglottic carcinoma. MATERIALS AND METHOD: A retrospective study was done on thirty-two patients who underwent a surgery or surgery with postoperative radiation therapy from 1990 to 2000. Neck dissection was performed in 27 patients and 24 patients received postoperative radiation therapy. RESULTS: The 3-year overall survival rate was 81.6%. The 3-year overall survival rate of T3 pure supraglottic carcinoma and T3 transglottic carcinoma were 91.7% and 73.2%, respectively (p<0.05). The univariate analysis revealed a prognostic significance for vocal cord fixation and statistical trend to age, dyspnea, clinical and pathological metastasis of cervical lymph node and postoperative radiation therapy (p<0.2). T3 transglottic carcinoma was significantly correlated with vocal cord fixation. CONCLUSION: Surgery or surgery with postoperative radiation therapy provides acceptable rates of cancer control and survival rate for patients with T3 supraglottic carcinoma. Transglottic involvement and vocal cord fixation shown by the fiberoptic laryngoscopy were significant prognostic factors. T3 transglottic cancer needs more aggressive management.
