An experimental study on the cytotoxicity of orthodontic wires.
- Author:
Yong Kyu LIM
1
;
Won Sik YANG
Author Information
1. Department of Dentistry, Seoul City Boramae Hospital, Korea.
- Publication Type:Original Article
- Keywords:
cytotoxicity;
orthodontic wire;
reaction index;
Ag-solder
- MeSH:
Agar;
Cell Culture Techniques;
Ethylene Oxide;
Fibroblasts;
Hot Temperature;
Humans;
Orthodontic Wires*;
Stainless Steel
- From:Korean Journal of Orthodontics
1996;26(5):591-599
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study was undertaken to investigate the cytotoxicity of orthodontic wires after doing various treatments to the wires. 018x025 inch Stainless steel(A) and Co-Cr(B) wires were used and each of them were divided into 4 groups. A-1 and B-1 groups were as received state, and A-2 and B-2 groups were heat treated. A-3 and B-3 groups were electropolished after heat treatment, and A-4 and B-4 groups were soldered with Ag-solder. Each group had 3 wires and these were sterilized with Ethylene Oxide gas. We used human gingival fibroblast cell culture and agar overlay technique to investigate the cytotoxicity of each group of wires. The cytotoxicity of wire was assessed using reaction index (zone index / lysis index). The findings of this study were as follows: 1. Both of the stainless steel wire and Co-Cr wire showed no cytotoxicity in as received state. 2. Heat treatment or electropolishing of the wires had no effect on the cytotoxicity of the wires. 3. Soldered stainless steel wires showed a little wider zone of discoloration than soldered Co-Cr wires, but the zone index and cytotoxicitytreaction index) was not different. 4. Soldered wires showed moderate cytotoxicity in both of the wires.