Parry-Romberg Syndrome Associated with Hypothyroidism.
10.3341/jkos.2017.58.7.857
- Author:
Yeon Hee LEE
1
;
Seong Eun LEE
;
Jung Yeul KIM
;
Kyoung Nam KIM
;
Sung Bok LEE
Author Information
1. Department of Ophthalmology, Chungnam National University School of Medicine, Daejeon, Korea. sblee@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Parry-Romberg syndrome;
Progressive facial hemiatrophy
- MeSH:
Adult;
Alopecia;
Antibodies, Antinuclear;
Atrophy;
Biopsy;
Enophthalmos;
Facial Hemiatrophy*;
Female;
Forehead;
Hematologic Tests;
Humans;
Hypothyroidism*;
Ocular Motility Disorders;
Orbit;
Rare Diseases;
Scalp;
Scleroderma, Localized;
Subcutaneous Tissue;
Thyroid Gland;
Thyroiditis;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2017;58(7):857-861
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We report a case of Parry-Romberg syndrome associated with right enophthalmos, hypotropia, up-gaze limitation, en coup the sabre, morphea, and hypothyroidism. CASE SUMMARY: A 41-year-old woman presented with slowly progressive right enophthalmos that started 5 years previous. With a Hertel exophthalmometer, the right eye measured 10 mm, and the left eye 13 mm. Right enophthalmos and atrophy of subcutaneous tissues of right side orbit were observed. Axial scan of computerized tomography shows atrophy of right side orbital subcutaneous tissues without bony abnormality. At primary gaze, 4 prism diopter hypotropia was observed in the right eye. Up-gaze was limited in both eyes. Visual acuity was 1.0 in both eyes. No specific sign was found in her anterior segment. The patient had experienced right side alopecia 20 years prior and had undergone biopsy, which proved morphea. Linear en coup de sabre morphea was found on the right forehead and scalp. Hypothyroidism due to Hashimoto's thyroiditis was diagnosed based on a blood test, which also showed positive antinuclear antibody. Thus, the patient was diagnosed with Parry-Romberg syndrome associated with hypothyroidism. CONCLUSIONS: Clinicians need to consider the rare disease Parry-Romberg syndrome when a patient with ophthalmologic symptoms such as enopthlamos or eye movement disorders is accompanied by dermatologic symptoms such as linear en coup de sabre morphea or alopecia.
