Treatment of Carbon Monoxide Poisoning with Therapeutic Hypothermia.
10.4266/kjccm.2013.28.3.218
- Author:
Young Hwan LEE
1
;
You Dong SOHN
;
Seung Min PARK
;
Won Wong LEE
;
Ji Yun AHN
;
Hee Cheol AHN
Author Information
1. Department of Emergency Medicine, Hallym University Sacred Heart Hospital, Hallym University School of Medicine, Anyang, Korea. hwaniyo@naver.com
- Publication Type:Case Report
- Keywords:
carbon monoxide;
complication;
induced hypothermia;
poisoning
- MeSH:
Anoxia;
Blood Pressure;
Body Temperature;
Carbon;
Carbon Monoxide;
Carbon Monoxide Poisoning;
Carboxyhemoglobin;
Coma;
Emergencies;
Heart Rate;
Humans;
Hypothermia;
Hypothermia, Induced;
Respiratory Rate;
Vital Signs
- From:The Korean Journal of Critical Care Medicine
2013;28(3):218-220
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carbon monoxide (CO) is a well-known chemical asphyxiant, which causes tissue hypoxia with prominent neurological injury. Therapeutic hypothermia (TH) has been shown to be an effective neuroprotective method in post-cardiac arrest patients. A 26-year-old man presented to the emergency department with severe CO poisoning. On arrival, the patient was comatose. His vital signs were blood pressure, 130/80 mm Hg; heart rate, 126/min; respiratory rate, 26/min; body temperature, 36degrees C; and O2 saturation, 94%. Initial carboxyhemoglobin was 45.2%. Because there was no available hyperbaric chamber in our local area, he was intubated and treated with TH. The target temperature was 33 +/- 1degrees C for 24 hours using an external cooling device. The patient was then allowed to reach normothermia by 0.15-0.25degrees C/hr. The patient was discharged after normal neurological exams on day 11 at the hospital. TH initiated after exposure to CO may be an effective prophylactic method for preventing neurological sequelae.