Effect of Amniotic Membrane Transplantation on Tissue Adhesion in Flexor Tenorrhaphy of Chicken.
10.4055/jkoa.2005.40.6.757
- Author:
Sung Hoo KIM
1
;
Lih WANG
;
Myung Jin LEE
;
Sung Soo KIM
;
Mee Sook ROH
Author Information
1. Department of Orthopedic Surgery, College of Medicine, Dong-A University, Busan, Korea. tynitus@dau.ac.kr
- Publication Type:Original Article
- Keywords:
Flexor tenorrhaphy;
Irradiated amniotic membrane;
Tissue adhesion
- MeSH:
Amnion*;
Chickens*;
Fibroblasts;
Fibrosis;
Inflammation;
Tendons;
Tissue Adhesions*
- From:The Journal of the Korean Orthopaedic Association
2005;40(6):757-762
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The role of the amniotic membrane with or without radiation was investigated with regard to preventing adhesion after flexor tenorrhaphy of chicken. MATERIALS AND METHODS: Nine chicken were divided into three groups. The second flexor tendon of the chicken was operated on. In group A, the flexor tendon was excised and one half and the tendon was repaired. In group B, the repaired tendon was covered with an amniotic membrane. In group C, the repaired tendon was covered with a lyophilised and 25 kGy irradiated amniotic membrane. The gross and histology findings on the level of inflammation and fibrosis of the repaired tendon were evaluated at 3, 6 and 9 weeks after surgery. RESULTS: Group C had the least inflammatory cell infiltration and fibroblast proliferation at any time. CONCLUSION: The use of radiated amniotic membrane was effective in preventing inflammation and adhesion after flexor tenorrhaphy in chickens.
