Clinical Manifestation and Treatment Outcomes of Nasal Cavity & Ethmoid Sinus Squamous Cell Carcinoma.
- Author:
Myung Whan SUH
1
;
Si Whan KIM
;
Yong Min KIM
;
Tae Bin WON
;
Chae Seo RHEE
;
Chul Hee LEE
;
Yang Gi MIN
Author Information
1. Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul, Korea. csrhee@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Carcinoma;
Squamous cell;
Nasal cavity;
Paranasal sinuses;
Survival rate
- MeSH:
Carcinoma, Squamous Cell*;
Disease-Free Survival;
Epistaxis;
Ethmoid Sinus*;
Humans;
Maxillary Sinus;
Nasal Cavity*;
Nasal Obstruction;
Paranasal Sinuses;
Prognosis;
Recurrence;
Survival Rate;
Treatment Outcome
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2007;50(3):215-219
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: We aimed to evaluate the clinical manifestation and treatment outcome of the nasal cavity squamous cell carcinoma (SCC) and compared its survival rate with that of the maxillary sinus (MS) SCC. SUBJECTS AND METHOD: Thirty two patients who were diagnosed as nasal cavity SCC or ethmoid sinus SCC between 1984 and 2005 were selected. These patients were referred to as the intranasal (IN) SCC group. Ten prognostic factors were evaluated in terms of survival rate and recurrence. The survival rate of 61 patients who were diagnosed as MS SCC was compared with that of the IN SCC. RESULTS: Chief complaints of the patients with IN SCC were nasal obstruction (40.4%), epistaxis (25.0%), and rhinorrhea (13.5%). The 5 year survival rate of IN SCC was 44.6% and the 5 year disease free survival rate was 27.7%. The most important prognostic factor was T stage (p<.001). The 5 year survival rate of MS SCC was 55.4%, and it was statistically not different from that of the IN SCC (p=.472). In the T1, T2, T3 stages, the 5-year-survival rate of the IN SCC was similar to that of MS SCC (p=.637). But in the T4 stage, IN SCC tended to have a worse prognosis (p=.074). CONCLUSION: The prognosis of IN SCC was similar to that of the MS SCC. However, MS SCCs were detected in a more advanced stage and T4 stage of the IN SCC had a worse prognosis compared to the same stage of MS SCC.
