A Case of Adenosqumous Carcinoma Ex Pleomorphic Adenoma of Hard Palate.
- Author:
Young Mo KIM
1
;
Jung Il CHO
;
Seung Joon LEE
;
Joon Mee KIM
Author Information
1. Department of Otorhinolaryngolgy-Head and Neck Surgery, Inha University College of Medicine, Inchon, Korea.
- Publication Type:Case Report
- Keywords:
Adenosquamous carcinoma;
Hard palate
- MeSH:
Adenocarcinoma;
Adenoma, Pleomorphic*;
Biopsy;
Carcinoma, Adenosquamous;
Carcinoma, Squamous Cell;
Diagnosis;
Humans;
Hyalin;
Male;
Middle Aged;
Neck;
Necrosis;
Neoplasm Metastasis;
Palate, Hard*;
Ulcer
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2001;44(11):1231-1234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carcinoma ex pleomorphic adenoma is a carcinoma that shows histologic evidence of arising in or from a preexisting benign mixed tumor. We experienced a case of carcinoma ex pleomorphic adenoma arising in the hard palate with neck metastatasis. The patient was 48-year-old male presenting ovoid elevated palatal mass that has been present for 25 years and rapid growing left neck mass for 3 months. The overlying mucosal surface was ulcerated. The tumor was well marginated but focally tightly adherent to the adjacent tissue. The initial pathologic diagnosis of open biopsy specimen was invasive squamous cell carcinoma. After the total removal, the histologic examination revealed that the tumor was composed of adenosquamous carcinoma and benign pleomorphic adenoma. The adenosquamous carcinoma, where grandular and epithelial differentiation were seen in the same clump of cells, showed extensive stromal hyalinization with necrosis and calcification. The metastatic neck lesion showed only squamous cell carcinoma component without adenocarcinoma. We present a case of an unusual carcinoma ex pleomorphic adenoma with adenosquamous cell carcinoma in the hard palate and neck metastasis.
