Immunohistochemical Analysis of Calretinin and Parvalbumin in the Goat Main Olfactory Bulb.
- Author:
Jung Hoon CHOI
1
;
Choong Hyun LEE
;
In Koo HWANG
;
Ki Yeon YOO
;
Yeo Sung YOON
;
Hyung Cheul SHIN
;
In Se LEE
;
Moo Ho WON
Author Information
1. Department of Anatomy and Neurobiology, and Institute of Neurodegeneration and Neuroregeneration, College of Medicine, Hallym University, Chuncheon 200-702, Korea.
- Publication Type:Original Article
- Keywords:
Calcium-binding proteins;
Goat;
Immunohistochemistry;
Olfaction;
Olfactory bulb
- MeSH:
Animals;
Calcium-Binding Protein, Vitamin D-Dependent;
Calcium-Binding Proteins;
Goats;
Immunohistochemistry;
Interneurons;
Neurons;
Olfactory Bulb;
Olfactory Nerve;
Smell
- From:Korean Journal of Anatomy
2009;42(2):115-122
- CountryRepublic of Korea
- Language:English
-
Abstract:
The distributions of calretinin (CR)- and parvalbumin (PV)-immunoreactive neurons in the main olfactory bulb (MOB) of the goat were examined in this study. As in other animals, the goat MOB has a characteristic laminar structure with laminar types and distribution patterns in each layer. CR-immunoreaction was observed in all layers of the MOB, except for the olfactory nerve layer. Most of CR-immunoreactive neurons were observed in the glomerular and granule cell layers. Relatively small number of CR-immunoreactive neurons was detected in other layers. These CR-immunoreactive neurons were interneurons. PV-immunoreaction was detected in all layers. In contrast to CR, olfactory nerve bundles were immunostained with PV. Most of PV-immunoreactive neurons were distributed in the glomerular and granule cell layers. PV-immunoreactive neurons were interneurons. This result suggests that CR and PV may play important roles in the olfactory signal modulation through interneurons in the goat MOB.
