Efficiency of Matricaria chamomilla CH(12) and number of doses of rabies vaccine on the humoral immune response in cattle.
- Author:
Luis Souza DE SOUZA REIS
1
;
Neuza Maria FRAZATTI-GALLINA
;
Rosana DE LIMA PAOLI
;
Rogerio GIUFFRIDA
;
Avelino ALBAS
;
Eunice OBA
;
Paulo Eduardo PARDO
Author Information
- Publication Type:Case Report ; Randomized Controlled Trial
- Keywords: cattle; immune response; Matricaria chamomilla; rabies; vaccine
- MeSH: Animals; Antibodies, Viral/blood; Cattle; Dose-Response Relationship, Immunologic; Drug Administration Schedule; Drug Interactions; Matricaria/*chemistry; Plant Extracts/chemistry/*pharmacology; Rabies Vaccines/administration & dosage/*immunology
- From:Journal of Veterinary Science 2008;9(4):433-435
- CountryRepublic of Korea
- Language:English
- Abstract: This study evaluated the effect of Matricaria chamomilla and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without Matricaria chamomilla CH(12) and vaccinated with one or two doses of rabies vaccine (30 day interval). No effect of chamomile was found on cattle immunization against rabies; however, antibody titers were protective in cattle vaccinated twice, while 93.3% of cattle vaccinated only once had titers under 0.5 UI/ml after 60 days. In conclusion, the use of chamomile did not alter the humoral immune response in cattle, and two vaccine doses are suggested for achieving protective antibody titers.
