Combination Therapy with Endoscopic Removal and Ambisome for Rhinocerebral Aspergillosis Invading Frontal Lobe: Report of a Case.
- Author:
Han Sung JANG
1
;
Min Sik KIM
;
Seong Jun WEE
;
Nam Su LEE
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, The Catholic University of Korea, College of Medicine, Seoul, Korea. jhsent@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Invasive aspergillosis;
Frontal sinus;
Endoscopic transnasal approach
- MeSH:
Amphotericin B;
Antifungal Agents;
Aspergillosis*;
Craniotomy;
Frontal Lobe*;
Frontal Sinus;
Immunocompromised Host
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2002;45(2):182-186
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The rhinocerebral aspergillosis invading sinuses and CNS is known to be a fatal desease in immunocompromised patients. The management principle of rhinocerebral aspergillosis is often by extensive surgical removal through craniotomy combined with amphotericin B therapy, and endoscopic removal had not been reported until now. We report in this study a case of rhinocerebral aspergillosis invading the left frontal sinus and the left frontal lobe which were treated by the combination therapy of endoscopic removal and antifungal agents.
