Oral Microbiome and Its Association with Oral Diseases.
10.3342/kjorl-hns.2016.17230
- Author:
Minsu KWON
1
Author Information
1. Department of Otorhinolaryngology, Eulji Medical Center, Eulji University, School of Medicine, Seoul, Korea. minsu014@gmail.com
- Publication Type:Review
- Keywords:
Cancer;
Head and neck;
Microbiome;
Oral cavity;
Oral mucositis
- MeSH:
Foreign Bodies;
Homeostasis;
Human Body;
Humans;
Microbiota*;
Mouth;
Otolaryngology;
Risk Factors;
Smoke;
Smoking;
Stomatitis
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2017;60(2):49-54
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Microbiome means a holistic genomic information of microorganism which usually having symbiotic relationships confer benefits to human body. Breaches in the homeostasis between host and microorganism or alterations of the microbiome are well-known risk factors promoting human diseases. Oral cavity has hundreds of microbes and demonstrates chronic inflammatory conditions by interrelations among microorganisms, foreign bodies, alcohol, and smoking. Oral microbiome also demonstrates a growing evidence of its implication in the etiology of oral diseases including cancer and other systemic diseases. In this review paper, I would introduce to the associated human diseases with oral microbiome and the mechanism how changes in the oral microbiome with its microenvironment leads to the host diseases. And I would also suggest a new research field in otorhinolaryngology connected to oral microbiome.
