Histopathologic Changes in Submandibular Sialolithiasis.
- Author:
Byung Joo LEE
1
;
Cheol Ju SEO
;
Il Woo LEE
;
Jae Woo LEE
;
Soo Geun WANG
;
Jee Yeon KIM
Author Information
1. Department of Otolaryngology, College of Medicine, Pusan National University, Busan, Korea.
- Publication Type:Original Article
- Keywords:
Submandibular gland;
Salivary gland claculi
- MeSH:
Anti-Bacterial Agents;
Atrophy;
Fibrosis;
Humans;
Inflammation;
Retrospective Studies;
Salivary Gland Calculi*;
Submandibular Gland
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2003;46(1):63-67
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: There are a few reports about the function of submandibular gland obstructed by stone. The purpose of this study was to evaluate the histopathologic change of submandibular gland for sialolithiasis and its correlation to histopathologic grades and clinical findings. MATERIALS AND METHODS: Retrospectively, we reviewed the clinical history of 23 patients who underwent submandibular gland excision for sialolithiasis. Histopathologic grades of submandibular gland were estabilished by the degrees of inflammation, atrophy, and fibrosis. We evaluated the relation between histopathologic grades and clinical findings including age, sex, duration of symptoms, number of infectious episodes, time between the last infectious episode and surgery, use of antibiotics. RESULTS: Normal to mild histopathologic grades showed 22% (5/23), the moderate grade showed 35% (8/23), the severe grade showed 43% (10/23). There is no significant relationship between histopathologic grades and clinical findings. CONCLUSION: The results of this study suggest that, if possible, the conservative therapy should be preferred rather than performing the excision of submandibular gland for sialolithiasis.