The Effectiveness of C-Reactive Protein Surveillance as a Method to Monitor the Post-Operative Antibiotics Administration after Total Knee Replacement Arthroplasty.
10.4055/jkoa.2012.47.3.171
- Author:
Hyun Jong BONG
1
;
Jun Ki MOON
;
Jin Kyu LEE
;
Choong Hyeok CHOI
Author Information
1. Department of Orthopedic Surgery, College of Medicine, Hanyang University, Seoul, Korea. chhchoi@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
knee;
antibiotic prophylaxis;
C-reactive protein (CRP);
total knee replacement arthroplasty
- MeSH:
Anti-Bacterial Agents;
Antibiotic Prophylaxis;
Arthroplasty;
Arthroplasty, Replacement, Knee;
C-Reactive Protein;
Humans;
Knee;
Organothiophosphorus Compounds;
Prospective Studies
- From:The Journal of the Korean Orthopaedic Association
2012;47(3):171-177
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the effectiveness of using C-reactive protein (CRP) surveillance as a method to monitor the effect of postoperative antibiotics for the prevention of early infection after total knee replacement arthroplasty (TKRA). MATERIALS AND METHODS: A prospective study was performed in 115 primary TKRAs. We examined the values of CRP of all cases on the 3rd, 5th, 7th, 10th and 14th days post-operatively. Some patients were administrated additional antibiotics under certain specific situations based on the pattern of CRP. The patients were divided into two groups: group I with planned period of administration and group II with administration longer than the planned period. RESULTS: No acute infection after TKRA due to CRP surveillance was observed. The mean duration of antibiotics administration was 5.9 days in all cases, 5 days in group I and 13.3 days in group II. Twelve cases (10.4%) were included in group II. The CRP was increased on the 5th and 10th days after operation in group II. CONCLUSION: The surveillance of CRP was thought to be helpful in monitoring the effects of post-operative antibiotics and prevention of early infection after TKRA.
