Calcineurin Inhibitor Induced Multiple Infarctions.
10.4285/jkstn.2016.30.4.190
- Author:
Hae Bong JEONG
1
;
Jeong Min KIM
;
Il Han YU
;
Jae Han BAE
;
Oh Sang KWON
;
Kwang Yeol PARK
Author Information
1. Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea. bellokim1@gmail.com
- Publication Type:Case Report
- Keywords:
Tacrolimus;
Acute cerebral infarction;
Kidney transplantation
- MeSH:
Brain;
Calcineurin*;
Cerebral Infarction;
Embolism;
Female;
Follow-Up Studies;
Humans;
Infarction*;
Kidney Transplantation;
Leg;
Magnetic Resonance Imaging;
Middle Aged;
Tacrolimus
- From:The Journal of the Korean Society for Transplantation
2016;30(4):190-193
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tacrolimus is the most commonly used immunosuppressant after kidney transplantation. Here, we report a patient with multiple cerebral infarctions during tacrolimus treatment after kidney transplantation. A 54-year-old female was admitted due to sudden onset right leg weakness. Brain magnetic resonance imaging (MRI) showed multiple acute infarctions but normal vasculature. Evaluations of cardiac embolism were unremarkable. After 8 months, her weakness progressed and follow-up brain MRI showed additional multiple infarctions. We changed here medication from tacrolimus to mycophenolate mofetil, and her symptoms improved gradually.
