Double Immunohistochemical Studies on Distribution and Coexistence with Putative Neurotransmitters and Calretinin in Trigeminal Ganglion of Korean Native Goat.
- Author:
Heungshik S LEE
1
;
In Se LEE
;
Jehoon SEO
Author Information
1. College of Veterinary Medicine, Seoul National University, Korea.
- Publication Type:Original Article
- Keywords:
Korean native goat;
trigeminal ganglion;
immunohistochemistry;
neurotransmitter;
calretinin
- MeSH:
Calbindin 2*;
Calcitonin Gene-Related Peptide;
Galanin;
Goats*;
Immunohistochemistry;
Neurons;
Neurotransmitter Agents*;
Substance P;
Trigeminal Ganglion*
- From:Korean Journal of Anatomy
1998;31(3):387-396
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The present study was undertaken to investigate the morphological characteristics of trigeminal ganglion in Korean native goat (Capra hircus) by immunohistochemical methods. The calcitonin gene-related peptide (CGRP), substance P (SP), galanin (GAL) and calretinin (CR) immunoreactivities by immunohistochemical method were observed in the neurons of trigeminal ganglion with populations of 43.75%, 26.01%, 4.98%, and 14.33%, respectively. In double immunohistochemical study, CGRP immunoreactivity was proven to be present in SP (93.93%) and GAL (100%) immunoreactive neurons. SP immunoreactivity was observed in CGRP (36.12%) and GAL (100%) immunore-active neurons. GAL immunoreactivity was colocalized with 8.14% of CGRP and 15.47% of SP immunoreactive neurons. However, CR immunoreactivity was not observed in CGRP, SP and GAL immunoreactive neurons. These findings exhibit that Korean native goat differs from other mammalian species in the distribution and localization of neurochemical substances in trigeminal ganglion, and suggest that these differences may be related with neuroanatomical characteristics.
