A Case of Hereditary Hemorrhagic Telangiectasia Managed with Intranasal Topical Estrogen.
- Author:
Jung Whan SONG
1
;
Hyun Jun KIM
;
Yong Ro YOON
;
Yun Tae KIM
Author Information
1. Department of Otolaryngology, Ajou University School of Medicine, Seoul, Korea. entkhj@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Hereditary hemorrhagic telangiectasia;
Epistaxis;
Estrogen
- MeSH:
Aged;
Blood Vessels;
Epistaxis;
Estrogens*;
Female;
Hemorrhage;
Humans;
Melena;
Mucous Membrane;
Quality of Life;
Skin;
Telangiectasia, Hereditary Hemorrhagic*;
Telangiectasis;
Viscera
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2006;49(4):447-450
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder affecting blood vessels of the skin, mucous membrane and viscera. It is characterized by a clinical triad of multiple telangiectasia, recurrent hemorrhages and familial occurrence. In 80% of patients, epistaxia is the first presenting symptom. It can have a massive impact on the quality of life of those affected. Otolaryngologists should be familiar with this disease because of its potential systemic complication. Recently, we have experienced a 69 year old female complaining of melena and recurrent epistaxis for 20 years. Epistaxis was successfully managed with topical estrogen ointment.
