Treatment Outcomes of Transurethral Macroplastique Injection for Postprostatectomy Incontinence.
10.4111/kju.2014.55.3.182
- Author:
Sin Woo LEE
1
;
Jung Hun KANG
;
Hyun Hwan SUNG
;
U Seok JEONG
;
Young Suk LEE
;
Minki BAEK
;
Kyu Sung LEE
Author Information
1. Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. ksleedr@skku.edu
- Publication Type:Original Article
- Keywords:
Dimethylpolysiloxanes;
Male;
Prostate;
Urethra;
Urinary incontinence
- MeSH:
Dimethylpolysiloxanes;
Follow-Up Studies;
Humans;
Male;
Methods;
Prostate;
Prostatic Hyperplasia;
Prostatic Neoplasms;
Retrospective Studies;
Urethra;
Urinary Incontinence;
Urinary Retention
- From:Korean Journal of Urology
2014;55(3):182-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We investigated the efficacy of transurethral injection of Macroplastique bulking agent (Uroplasty) for male stress urinary incontinence (SUI) after prostate surgery. MATERIALS AND METHODS: This retrospective review included men with SUI treated by transurethral injection for symptoms resulting from prostate surgery. Patients were evaluated at 1 month and 6 months after injection by determining the number of pads used per day and changes in incontinence symptoms. Treatment success was defined as use of 1 pad or fewer per day combined with subjective symptom improvement. RESULTS: The study population comprised 30 men with a mean age of 66.1+/-5.3 years. Of the 30 patients, 24 (80.0%) underwent prostate cancer surgery and the remaining 6 (20.0%) underwent surgery for benign prostatic hyperplasia. The preinjection pad number was 2.9+/-1.9 pads per day. After injection treatment, the mean follow-up period was 9.3+/-12.7 months and the success rate was 43% (13/30) at 1 month and 32% (6/19) at 6 months. Injection was more likely to result in a successful outcome in patients with no preinjection radiation treatment history and higher abdominal leak point pressure (ALPP) than in those with a previous history of radiation treatment and lower ALPP, although this result was not statistically significant. Acute urinary retention occurred in 5 patients (17%). CONCLUSIONS: Transurethral Macroplastique injection treatment is a relatively non-invasive treatment method for male SUI with a success rate of 43% at 1 month and 32% at 6 months. Patients with a higher ALPP and no previous history of radiation therapy may experience better treatment outcomes.
