Trial of Oral Metoclopramide on Diurnal Bruxism of Brain Injury.
10.5535/arm.2013.37.6.871
- Author:
Ho Sung YI
1
;
Hyoung Seop KIM
;
Mi Ri SEO
Author Information
1. Department of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Bruxism;
Dopamine receptors;
Metoclopramide
- MeSH:
Braces;
Brain Injuries*;
Brain*;
Bromocriptine;
Bruxism*;
Frontal Lobe;
Humans;
Metoclopramide*;
Positron-Emission Tomography;
Prefrontal Cortex;
Receptors, Dopamine;
Stroke;
Tooth
- From:Annals of Rehabilitation Medicine
2013;37(6):871-874
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bruxism is a diurnal or nocturnal parafunctional activity that includes tooth clenching, bracing, gnashing, and grinding. The dopaminergic system seems to be the key pathophysiology of bruxism and diminution of dopaminergic transmission at the prefrontal cortex seems to induce it. We report two patients with diurnal bruxism in whom a bilateral frontal lobe injury resulted from hemorrhagic stroke or traumatic brain injury. These patients' bruxism was refractory to bromocriptine but responded to low-dose metoclopramide therapy. We propose that administering low doses of metoclopramide is possibly a sound method for treating bruxism in a brain injury patient with frontal lobe hypoperfusion on positron emission tomography imaging.
