A Clinical Study of Histiocytic Necrotizing Lymphadenitis(Kikuchi's Disease).
- Author:
Ki Hwan HONG
1
;
Kwang Min KIM
;
Jeong Hun PARK
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Chonbuk National University, Chonju, Korea. Khhong@chonbuk.moak.ac.kr
- Publication Type:Original Article
- Keywords:
Histiocytic necrotizing lymphadenitis;
Kikuchi's disease;
Open biopsy;
Fine needle aspiration cytology
- MeSH:
Biopsy;
Biopsy, Fine-Needle;
Blood Sedimentation;
Chills;
Diagnosis;
Female;
Fever;
Histiocytic Necrotizing Lymphadenitis;
Humans;
Leukopenia;
Lymph Nodes;
Lymphatic Diseases;
Male;
Recurrence;
Sweat;
Treatment Outcome
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
1999;42(4):490-494
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: The origin and clinical characteristic of histiocytic necrotizing lymphadenitis (HNL), or Kikuchi's disease, are not well-known. This report was conducted to investigate clinical characteristics and treatment outcome in order to contribute to the diagnosis and treatment of HNL. MATERIALS AND METHODS: We reviewed 28 patients with HNL by open biopsy during the past 8 years beginning January 1990 to December 1997 for the analysis of clinical features. RESULTS: 1) It occurred more often in females (17 cases: 61%) than males (11 cases: 39%). 2) It was seen relatively more often in the second decades showing 14 cases (50%). 3) Cervical lymphadenopathy appeared most common initial manifestation (16 cases: 57%), followed by cervical adenopathy with fever (12 case: 43%). 4) Cervical lymphadenopathy were usually multiple (22 cases; 79%) and tender (26 cases: 93%) rather than solitary (6 cases: 21%) and non-tender (2 cases: 7%) and in addition to cervical lymphadenopathy, some cases showed axillary and inguinal lymphadenopathy (2 cases: 7%). 6) Leukopenia and elevated erythrocyte sedimentation rates appeared most frequently in the abnormal laboratory data (16 cases: 57%). 7) Most patients recovered with the conser-vative treament and there was no specific complicatons and recurrence. CONCLUSION: We should consider open biopsy or fine needle aspiration cytology of lymph node in patients who have cervical adenopathy with fever, chills, night sweats, especially young women under the 30 years.
