Cytogenetic Analysis of Squamous Cell Carcinoma of the Lung.
- Author:
Seung Je JO
- Publication Type:Original Article
- Keywords:
Cytogenetif analysis;
Chromsomal abnormality
- MeSH:
Carcinoma, Squamous Cell*;
Chromosome Aberrations;
Chromosomes, Human, Pair 1;
Chromosomes, Human, Pair 22;
Cytogenetic Analysis*;
Cytogenetics*;
Lung*;
Monosomy;
Sex Chromosomes;
X Chromosome;
Y Chromosome
- From:Korean Journal of Anatomy
1997;30(5):567-574
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The cytogenetic study of 3 cases of squamous cell carcinoma of the lung was performed to identify chromosomal abnormalities. All tumor cells were hypodiploid state on the average. Specicfic chromosomal anomalies were del[4][q33] and del[6][q25] in case 1, i[21q] in case 2, and del[3][q12] in case 3. The tendencies of monosomy were appered at chromosome 1, 9, 17, 18, 19, 22, and X chromosome in case 1, chromosome 22 and Y chromosome in case 2, and chromosome 1, 9, 16, 19, 20, 21, 22 and Y chromosome in case 3. The losses of sex chromosomes and chromosome 22 were common in these cases.
