Correlation between Bone Mineral Density and Knee Osteoarthritis.
10.4055/jkoa.2002.37.6.718
- Author:
Woo Nam MOON
1
;
Kyung Sang LEE
Author Information
1. Department of Orthopedic Surgery, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University, School of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Knee;
Osteoarthritis;
Bone mineral density
- MeSH:
Bone Density*;
Female;
Hip;
Humans;
Knee Joint;
Knee*;
Osteoarthritis;
Osteoarthritis, Knee*;
Spine;
Weight-Bearing
- From:The Journal of the Korean Orthopaedic Association
2002;37(6):718-722
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To examine the correlation between bone mineral density (BMD) and radiographic changes in knee osteoarthritis (OA). MATERIALS AND METHODS: BMD of the lumbar spine and hip was measured, using dual x-ray energy absorptiometry, in 297 Korean women who visited our clinic with knee joint pain; anteroposterior weight bearing X-ray of the knees was also taken. Radiographic OA was defined as a Kellgren-Lawrence score of >or=2. The relationship between BMD and the radiographic changes of OA was examined using correlation and multiple regression analysis. RESULTS: Mean BMD was lower in subjects with knee OA (n=136) than in non OA subjects (n=161): Mean BMD in the lumbar spine, OA group was 0.863 +/-0.154 g/cm2 and in the non OA group 0.896 +/-0.131 g/cm2, and there was no significant correlation between the BMD of the spine and radiographic knee OA (r=-0.087, p=0.134). Mean BMD in the hip, OA group was 0.610 +/-0.135 g/cm2 and in the non OA group was 0.662+/-0.105 g/cm2, and the difference between the two groups was significant (r=-0.227, p<0.001). CONCLUSION: Hip BMD and radiographic knee OA were found to be negatively correlated, although the mechanism remains unclear. This result differs from that of a western study and further study is needed.
