A Case of NK/T Cell Lymphoma in Sinonasal Tract.
- Author:
Joong Ho AHN
1
;
Hyang Cho KIM
Author Information
1. Department of Otolaryngology, Pundang Jesaeng Hospital, Daejin Medical Center, Sungnam, Korea.
- Publication Type:Case Report
- Keywords:
Lymphoma;
Non-hodgkin;
Paranasal sinuses;
Neoplasms
- MeSH:
Aged;
Asia;
Drug Therapy;
Granuloma;
Humans;
Inflammation;
Lymphoma*;
Lymphoma, Non-Hodgkin;
Necrosis;
Paranasal Sinuses;
Phenotype;
Prognosis;
Radiotherapy
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2004;47(5):474-477
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary sinonasal NK/T cell lymphoma is relatively common in Asia than in Western countries, comprising up to 7% of all Non-Hodgkin's lymphoma with a marked preponderance demonstrating a NK/T-cell phenotype. Sinonasal NK/T cell lymphoma is typically associated with abundant crust on mucosal surface, widespread necrosis, and extensive inflammation. Sinonasal NK/T cell lymphoma is characterized by a progressive clinical course and poor prognosis, and histologically, it shows angioinvasion and necrosis. It is referred to by such terms as non-healing granuloma, lethal granuloma or midline granuloma. Treatment of NK/T cell lymphoma consists of radiotherapy, chemotherapy, or both. We experienced a case of sinonasal NK/T cell lymphoma in a 65 year old man who complained of periorbital swelling.
