Use of canine small intestinal submucosa allograft for treating perineal hernias in two dogs.
10.4142/jvs.2012.13.3.327
- Author:
A Jin LEE
1
;
Wook Hun CHUNG
;
Dae Hyun KIM
;
Kyung Pil LEE
;
Hyun Jung SUH
;
Sun Hee DO
;
Ki dong EOM
;
Hwi Yool KIM
Author Information
1. Department of Veterinary Surgery, College of Veterinary Medicine, Konkuk University, Seoul 143-701, Korea. hykim@konkuk.ac.kr
- Publication Type:Case Reports
- Keywords:
biomaterial scaffold;
canine small intestinal submucosa (canine SIS);
perineal hernia
- MeSH:
Animals;
Biocompatible Materials;
Dog Diseases/*surgery;
Dogs;
Hernia, Abdominal/surgery/*veterinary;
Herniorrhaphy/veterinary;
Intestinal Mucosa/*transplantation;
Intestine, Small/*transplantation;
Male;
Perineum/surgery;
Postoperative Complications/veterinary;
Transplantation, Homologous/veterinary
- From:Journal of Veterinary Science
2012;13(3):327-330
- CountryRepublic of Korea
- Language:English
-
Abstract:
Here, we describe two dogs in which canine small intestinal submucosa (SIS) was implanted as a biomaterial scaffold during perineal herniorrhaphy. Both dogs had developed severe muscle weakness, unilaterally herniated rectal protrusions, and heart problems with potential anesthetic risks. Areas affected by the perineal hernia (PH) located between the internal obturator and external anal sphincter muscles were reconstructed with naive canine SIS sheets. In 12 months, post-operative complications such as wound infections, sciatic paralysis, rectal prolapse, or recurrence of the hernia were not observed. Symptoms of defecatory tenesmus also improved. Neither case showed any signs of rejection or specific immune responses as determined by complete and differential cell counts. Our findings demonstrate that canine SIS can be used as a biomaterial scaffold for PH repair in dogs.
