Successful Brain Dead Donor Management with CRRT: A Case Report.
10.4266/kjccm.2012.27.4.286
- Author:
Sang Hyun LIM
1
;
Young Joo LEE
;
Han Bum JOE
;
Jae Moung LEE
;
In Kyung LEE
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Ajou University School of Medicine, Suwon, Korea.
- Publication Type:Case Report
- Keywords:
brain-dead donor;
continuous renal replacement therapy;
potential organ donor
- MeSH:
Blood Glucose;
Brain;
Brain Death;
Coma;
Death, Sudden, Cardiac;
Hemodiafiltration;
Hemorrhage;
Humans;
Intensive Care Units;
Kidney;
Lactic Acid;
Liver;
Male;
Potassium;
Renal Replacement Therapy;
Subarachnoid Hemorrhage;
Tissue Donors;
Vital Signs
- From:The Korean Journal of Critical Care Medicine
2012;27(4):286-289
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Brain death results in adverse pathophysiologic effects in many brain-dead donors with cardiovascular instability. We experienced a brain-dead donor with continuous renal replacement therapy (CRRT) who was in a severe metabolic, electrolyte derangement and poor pulmonary function. The thirty-nine-year-old male patient with subarachnoid hemorrhage and intraventricular hemorrhage was admitted into the intensive care unit (ICU). After sudden cardiac arrest, he went into a coma state and was referred to as a potential organ donor. When he was transferred, his vital sign was unstable even under the high dose of inotropics and vasopressors. Even with aggressive treatment, the level of blood sugar was 454 mg/dl, serum K+ 7.1 mEq/L, lactate 5.33 mmol/L and PaO2/FiO2 60.3. We decided to start CRRT with the mode of continuous venovenous hemodiafiltration (CVVHDF). After 12 hours of CRRT, vital sign was maintained well without vasopressors, and blood sugar, serum potassium and lactate levels returned to 195 of PaO2/FiO2. Therefore, he was able to donate his two kidneys and his liver.
