Korean Medication Algorithm for Depressive Disorder 2012 (III): The Subtypes of Depression.
- Author:
Young Min PARK
1
;
Won KIM
;
Eun Sung LIM
;
Hwang Bin LEE
;
Jong Hyun JEONG
;
Hoo Rim SONG
;
Jeong Seok SEO
;
Jeong Wan HONG
;
Hee Ryung WANG
;
Won Myong BAHK
;
Duk In JON
;
Jin Pyo HONG
;
Kyung Joon MIN
Author Information
1. Department of Psychiatry, Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.
- Publication Type:Original Article
- Keywords:
Korean medication algorithm;
Major depressive disorder;
Dysthymic disorder;
Subtype
- MeSH:
Antidepressive Agents;
Bupropion;
Depression;
Depressive Disorder;
Depressive Disorder, Major;
Dysthymic Disorder;
Fluoxetine;
Mianserin;
Postal Service;
Psychiatry;
Surveys and Questionnaires;
Seasons;
Serotonin;
Sertraline;
Thiophenes;
Duloxetine Hydrochloride
- From:Korean Journal of Psychopharmacology
2013;24(1):18-24
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Recently, the pharmacotherapy including antidepressants in treating depression is widely used. However, as a result of newer agents that are continuously introduced, pharmacological treatment strategy is also changing. To catch up this trend, Korean Medication Algorithm Project for Depressive Disorder was developed in 2002 and revised in 2006. Since the last revision, the third revision reflected the new research result and the latest trends in the areas of pharmacological treatment. METHODS: One hundred and twenty three psychiatrists who have vast clinical experiences in depressive disorder are primarily selected then survey was sent to them via mail, 67 surveys were retried. This survey is constructed with 44 questionnaires in which contained from overall treatment strategies to treatment strategies under the specific circumstances. Each treatment strategy or treatment option is evaluated with the overall score of nine and the following 95% confidence interval result treatment option were divided into three phases of recommendation; primary, secondary, tertiary. RESULTS: For dysthymic disorder, antidepressant monotherapy including selective serotonin reuptake inhibitor (SSRI) [(es)citalopram, fluoxetine, sertraline, paroxetine], serotonin-norepinephrine reuptake inhibitor (SNRI) (venlafaxine, duloxetine, milacipran), and mirtazapine, was recommended as the first line medications. For melancholic type, SSRI, SNRI, and mirtazapine were recommended as the first line medications. For atypical type and seasonal pattern, bupropion as well as SSRI, SNRI, and mirtazapine, were recommended as the first line medications. CONCLUSION: The preferences of antidepressants in experts were different according to the subtype of depression. These results suggest that clinicians have to consider the subtype of depression in the treatment of depressive disorders.
