A Case of Herpes Simplex Meningoencephalitis with Broca's Aphasia.
- Author:
Hyung Joon YIM
1
;
Jin Soo LEE
;
Byung Won HUR
;
Jang Wook SOHN
;
Heong Jeong WOO
;
Hee Jin CHEONG
;
Woo Joo KIM
;
Min Ja KIM
;
Seung Chull PARK
Author Information
1. Depatment of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Herpes simplex meningoencephalitis;
Broca's aphasia
- MeSH:
Acyclovir;
Adult;
Aphasia*;
Aphasia, Broca;
Brain;
Diagnostic Tests, Routine;
Electroencephalography;
Encephalitis, Herpes Simplex*;
Fever;
Herpes Simplex*;
Humans;
Lip;
Magnetic Resonance Imaging;
Male;
Memory;
Mortality;
Nausea;
Neck;
Polymerase Chain Reaction;
Tomography, X-Ray Computed;
Vomiting
- From:Korean Journal of Infectious Diseases
1999;31(1):35-40
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Herpetic meningoencephalitis is a devastating disease with significant morbidity and mortality. One of the most serious clinical sequelae is aphasia, usually of sensory type, whereas, Broca's or motor aphasia is not a common manifestation. We report a case of herpetic meningoencephalitis diagnosed by polymerase chain reaction (PCR) and viral culture with Broca's aphasia as a neurologic sequela. A 35-year old male patient was admitted due to fever and altered mentality for 3 days. He was accompanied by nausea, vomiting, disorientation, and memory defect. Several vesicular eruptions were noted around the lips. Neck stiffness was present, but Kernig's and Brudzinski signs were not observed. Herpetic meningoencephalitis was confirmed with PCR and other diagnostic tests such as EEG, brain MRI, brain CT scan, and viral culture. His overall clinical condition was improved after acyclovir therapy, but Broca's aphasia remained as a sequela.
