The Effectiveness of the Sclerotherapy of Benign Neck Cyst with the Use of OK-432 and 99% Alcohol.
- Author:
Myung Gu KIM
1
Author Information
1. Department of Otorhinolaryngology-Head and Neck surgery, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Masan, Korea. mgent, kim@Samsung.net
- Publication Type:Original Article
- Keywords:
Sclerotherapy;
Ranula;
Lymphangioma;
Thyroglossal duct cyst;
Branchial cleft cyst
- MeSH:
Branchioma;
Fever;
Humans;
Lymphangioma;
Neck*;
Picibanil*;
Ranula;
Retrospective Studies;
Sclerosing Solutions;
Sclerotherapy*;
Thyroglossal Cyst
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2005;48(9):1154-1160
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: In most cases of benign neck cysts, surgical excision has been considered the definite treatment. However, it is difficult to excise cysts completely in some cases. In view of this, non-surgical treatment for these lesions has been attempted with sclerosing agents. Some authors presented case reports on using OK-432 or 99% Alcohol sclerotherapy. In this study, we compared OK-432 and 99% Alcohol sclerotherapy with regards to effectiveness and complications associated in treating benign neck cyst. SUBJECTS AND METHOD: We retrospectively reviewed 29 patients who had undergone sclerotherapy with OK-432 or 99% Alcohol for benign neck cyst, such as ranula, lymphangioma, thyroglossal duct cyst and branchial cleft cyst. Information was gathered with respect to age, sex, number of injections, post-sclerotherapy side effects and outcome of treatments. RESULT: In the OK-432 sclerotherapy, 16 patients (69.6%) showed complete response, and 5 patients (20.7%) showed intermediate response. No response was seen in 2 patients (9.7%). In the 99% Alcohol sclerotherapy, 5 patients (83.3%) showed complete response, and 1 patient (16.7%) showed intermediate response. The side effects observed from intracystic injection therapy with OK-432 and 99% Alcohol were fever (55.2%) and localized pain (44.8%). In the OK-432 sclerotherapy, 18 patients (78.3%) had complications, In the 99% Alcohol, 3 patients (50%) had complications. However, these complications spontaneously disappeared after several days in all the cases. CONCLUSION: The results showed that OK-432 and 99% Alcohol injection is an effective and safe treatment for benign neck cyst. The effectiveness of OK-432 and 99% Alcohol injection is very similar.
