Changes of Ultrastructure and Atrial Specific Granules of Atrial Myocytes in Dehydrated and Rehydrated Rats.
- Author:
Hyoung Tae KIM
1
;
Hyu KIM
;
Chang Ho SONG
;
Eui Hyeog HAN
;
Moo Sam LEE
Author Information
1. Department of Anatomy and Institute for Medical Science Chonbuk National University Medical School, Korea. alms@chonbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Atrium;
Dehydration;
Rehydration;
Specific granule;
Ultrastructure
- MeSH:
Animals;
Dehydration;
Diet;
Fluid Therapy;
Microscopy, Electron, Transmission;
Mitochondria;
Muscle Cells*;
Myelin Sheath;
Myofibrils;
Rats*;
Rats, Sprague-Dawley;
Vacuoles;
Water
- From:Korean Journal of Anatomy
2001;34(6):567-578
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The ultrastructural changes of atrial myocytes were examined by transmission electron microscopy and ultrastructural morphometry by dehydrated and rehydrated rat. Sprague-Dawley rats weighting 210 to 240 gm were fed with dried diet and without water for 3, 7 and 9 days, and then with standard diet and tap water for 9 days. On day 7 of dehydration, morphological changes in atrial myocytes were mainly the alterations of mitochondria and myofibrils, and the appearance of vacuoles with myelin structures and vesicular typed granules. On day 9 of dehydration, cells containing the myelin structures were increased than those on day 7 of dehydration. On day 3 to 5 rehydration, many atrial myocytes were damaged. On day 9 rehydration, most atrial myocytes were similar to control groups. The numbers of atrial specific granules were increased in all dehydrated groups and decreased in 1 day and 3 day rehydrated groups then that of normal atria. The numbers of atrial specific granules were similar level to normal animals in 5 day and 9 day rehydrated groups.
