A study of osteonectin expression patterns in BAPN-induced cleft palate formed rats.
- Author:
Ki Chul TAE
1
;
En Chel KIM
;
Sun Kyeong LEE
Author Information
1. Department of Orthodontics, School of Dentistry, Wonkwang University, Korea.
- Publication Type:Original Article
- Keywords:
Western blot;
Cleft palate;
Osteonectin;
Immunohistostaln;
Western blot
- MeSH:
Animals;
Blotting, Western;
Body Weight;
Cleft Palate*;
Fetus;
Maxilla;
Osteonectin*;
Palate;
Pregnancy;
Rats*
- From:Korean Journal of Orthodontics
2000;30(4):433-440
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to investigate osteonectin expression patterns in cleft palatecompare to normal palate rats. We used 4 pregnant rats, and beta-aminoproprionitrile was oral dose to rat according to lg/kg body weight at gestation days 13 to induce cleft palate. Total 6 fetus was got with cleft formed, then 3 fetus was used for immunohistostain and 3 fetus was used for western blot analysis. Expression patterns of osteonectin in mesenchymal cells of cleft palate was more dilute to mesenchymal cells of normal palate with immnunohistostain, and width and length of band of maxilla in cleft palate was more thin than maxilla of normal palate with western blot study.
