Dapiprazole for the Reversal of Mydriasis.
- Author:
Jun Seok TAE
1
;
Jung Hyub OH
Author Information
1. Department of Ophthalmology, Seoul Adventist Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Dapiprazole;
Mydriasis
- MeSH:
Glare;
Humans;
Iris;
Mydriasis*;
Ophthalmic Solutions;
Phenylephrine;
Pupil;
Receptors, Adrenergic;
Tropicamide
- From:Journal of the Korean Ophthalmological Society
1993;34(11):1073-1078
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Some patients are very sensitive to glare after diagnostic mydriasis with tropicarnide or phenylephrine. It would be desirable to reverse the effects of mydriasis rapidly and safely after diagnostic mydriasis. We assessed the effect of topical dapiprazole, an alpha adrenergic receptor blocker, in reversing mydriasis in 40 dark brown Iris subjects who received tropicamide 1% or phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eyes that received dapiprazole and the control eyes. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instilation of tropicamide 1% or phenylephrine 2.5% into dark brown irides.
