Histopathologic Findings after Experimental Penetrating Keratoplasty using Dacron-Gore-Tex(R) Combined Graft in Rabbits: Treatment of Corneal Perforation using Synthetic Materials. Report II.
- Author:
Jong Kyu LEE
1
;
Kee Yong CHOI
;
Byung Joo YOON
Author Information
1. Department of Ophthalmology, National Medical Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Corneal perforation;
Dacron;
Fibrovascular invasion;
Gore-Tex(R) Lekage
- MeSH:
Anterior Chamber;
Corneal Perforation*;
Keratoplasty, Penetrating*;
Polyethylene Terephthalates;
Postoperative Period;
Rabbits*;
Transplants*
- From:Journal of the Korean Ophthalmological Society
1993;34(11):1093-1100
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study is to evaluate the histopathologic findings after experimental penetrating keratoplasty using Dacron-Gore-Tex(R) combined graft in rabbits and the clinical efficacy of the treatment of corneal perforation using synthetic materials. Type A which used end to end fixation showed better results than that of type B which used intralamellar fixation and, however, complications and instability of graft occured in most eyes of both types. Type C which modified type B and reduced the thickness of intralamellar portion of graft showed relatively good results compared with type A and B, but there was still instability. Leakage from anterior chamber in early postoperative period prior to fiibrovascular invasion into graft was considered as the main cause of instability of graft. Therefore we performed type D which emphasized on preventing leakage, and well-maintained anterior chamber without extrusion of graft, that is, the best result among all 4 types was observed until 6 weeks postoperatively. Although further study is needed, we think that Dacron-Gore-Tex(R) combined graft can be a good substitute for the management of corneal perforation.
