Histological Evaluation of Gore-Tex(R) used in Nasal Augmentation of Human.
- Author:
Chan Hum PARK
1
;
Duk Young KIM
;
Hyung Rho CHU
;
Jin Hyoung CHUN
;
Young Hee CHOI
;
Won Shil HUH
;
Hyoung Jin MOON
;
Dong Hak JUNG
Author Information
1. Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Hallym University, Chunchon, Korea. hlpch@lycos.co.kr
- Publication Type:Original Article
- Keywords:
Rhinoplasty;
Polytetrafluoroethylene;
Histology
- MeSH:
Child, Preschool;
Collagen;
Connective Tissue;
Foreign-Body Reaction;
Humans*;
Individuality;
Models, Animal;
Polytetrafluoroethylene;
Rhinoplasty
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2005;48(2):182-188
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: Although Gore-Tex is popularly used in nasal augmentation in human, studies about the histological changes have been carried out only in animal models. The purpose of this study is to investigate histological changes of Gore-Tex used in nasal augmentation in human. SUBJECTS AND METHODS: Gore-Tex of 24 patients who underwent nasal augmentation using Gore-Tex (non-reinforced sheets) 2-36 months ago and had re-operated for the sole cosmetic problems was obtained. Histologic examination was performed from specimens including Gore-Tex and the surrounding soft tissue with light microscope and electromicroscope. RESULTS: Histologically, connective tissue ingrowth was observed in all specimen. But the degree of foreign body reaction and collagen deposit varied from specimen to specimen and had no relationship with the duration. Neovascularization was observed from specimen whose duration was longer than 12 months and degenerative calcification was observed from 36 month old specimen. CONCLUSION: Unlike the findings of previous reports, individual differences and partial degenerative lesions in Gore-Tex were observed. Additional studies are required to confirm the stability of Gore-Tex as an implant to be used in human.
