Three Cases of Anticonvulsant Hypersensitivity Syndrome Associated with Lamotrigine.
- Author:
Yong Won CHO
1
;
Hyung LEE
;
Sung Il SOHN
;
Doo Kyo JUNG
;
Jeong Geun LIM
;
Sang Doe YI
Author Information
1. Department of Neurology, Keimyung University, School of Medicine, Korea. neurocho@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Anticonvulsant hypersensitivity syndrome;
Lamotrigine
- MeSH:
Anticonvulsants;
Eosinophilia;
Exanthema;
Fever;
Hypersensitivity*;
Leukopenia;
Lymphatic Diseases
- From:Journal of the Korean Neurological Association
2002;20(1):79-81
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Among the various side effects of anticonvulsant medication, the anticonvulsant hypersensitivity syndrome (AHS) is underrecognized. This condition developed frequently with aromatic anticonvulsants, but with new antiepileptic drugs as well. We experienced three lamotrigine-induced AHS cases with symptoms such as fever, rash, leukopenia, eosinophilia and lymphadenopathy, which subsided after withdrawal of lamotrigine.
