Seroprevalence of Brucellosis in Human Immunodeficiency Virus Infected Patients in Hamadan, Iran.
10.24171/j.phrp.2017.8.4.09
- Author:
Fariba KERAMAT
1
;
Mohammad Mehdi MAJZOBI
;
Jalal POOROLAJAL
;
Zohreh Zarei GHANE
;
Maryam ADABI
Author Information
1. Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. maryam_adabi@yahoo.com
- Publication Type:Original Article
- Keywords:
brucellosis;
human immunodeficiency virus;
serology
- MeSH:
Agglutination Tests;
Brucella;
Brucellosis*;
Causality;
CD4 Lymphocyte Count;
HIV Infections;
HIV*;
Humans*;
Iran*;
Mercaptoethanol;
Seroepidemiologic Studies*;
Serologic Tests
- From:
Osong Public Health and Research Perspectives
2017;8(4):282-288
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: Brucellosis is a systemic disease with a wide spectrum of clinical manifestations. This study aimed to determine the seroprevalence of brucellosis in human immunodeficiency virus (HIV) infected patients in Hamadan Province in the west of Iran. METHODS: A total of 157 HIV-infected patients were screened through standard serological tests, including Wright’s test, Coombs’ Wright test, and 2-mercaptoethanol Brucella agglutination test (2ME test), blood cultures in Castaneda media, and CD4 counting. Data were analyzed using Stata version 11. RESULTS: Wright and Coombs’ Wright tests were carried out, and only 5 (3.2%) patients had positive serological results. However, all patients had negative 2ME results, and blood cultures were negative for Brucella spp. Moreover, patients with positive serology and a mean CD4 count of 355.8 ± 203.11 cells/μL had no clinical manifestations of brucellosis, and, and the other patients had a mean CD4 count of 335.55 ± 261.71 cells/μL. CONCLUSION: Results of this study showed that HIV infection is not a predisposing factor of acquiring brucellosis.
