Clinical Application of Nanotechnology.
10.3342/kjorl-hns.2011.54.3.185
- Author:
Seung Kuk BAEK
1
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea. mdbsk@paran.com
- Publication Type:Review
- Keywords:
Nanotechnology;
Nanoparticles;
Drug delivery systems;
Laser therapy
- MeSH:
Drug Delivery Systems;
Early Detection of Cancer;
Humans;
Laser Therapy;
Molecular Imaging;
Nanoparticles;
Nanotechnology;
Radiation, Ionizing;
Sensitivity and Specificity
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2011;54(3):185-191
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The limitations of current modalities for diagnosis and treatment of various diseases including cancer have led to look for the method with more sensitivity or specificity and lower toxicity. The advance in nanobiotechnology has shown the possibility to get newer and improved diagnostic and treatment method. Especially, gold nanoparticles can be applied diagnostically for early detection of cancer cells by molecular imaging or therapeutically for drug delivery, including chemotherapeutic drugs, photothermal therapy, and ionizing radiation enhancement. This review discusses characteristics, action mechanisms, and clinical application of nanoparticle. Even if the safety of nanoparticles is not yet fully defined, there is no doubt that nanotechnology in the future may play an important role in the diagnosis and treatment of various human diseases.
